Magnesium Is Trending—but Are You Taking the Right Form

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Reading Time: 6 minutes

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Written By Mruga D. Apte, Nutrition Expert at Unbox Health

Magnesium is one of the most essential minerals in the human body required for over 300 enzymatic reactions including energy production, nerve conduction, muscle contraction, and even DNA synthesis [1]. While it’s encouraging to see magnesium trending across health circles, there’s one critical aspect that’s often overlooked: the form of magnesium you consume matters.

RDA Requirement for Magnesium [10]

According to the Indian Council of Medical Research (ICMR), the Recommended Dietary Allowance (RDA) for magnesium is:

  • 340 mg/day for adult women
  • 420 mg/day for adult men

 

These requirements reflect the essential role magnesium plays in supporting neuromuscular function, energy metabolism, sleep regulation, and cardiovascular health. Given that nearly 50% of the Indian population may be deficient in magnesium, meeting these targets through food becomes especially important.

Natural Sources of Magnesium

Several whole foods are naturally rich in magnesium and can help bridge dietary gaps. Below are some common magnesium-rich foods ranked by their magnesium content (per 100g), along with the percentage of the Indian RDA they fulfill:

FoodMagnesium (mg/100g)%RDA for Women%RDA for Men
Pumpkin Seeds592 mg174%141%
Flaxseeds392 mg115%93%
Sesame Seeds350 mg103%83%
Chia Seeds335 mg98%80%
CashewNuts292 mg86%70%
Almonds270 mg79%64%
Spinach (cooked)~ 87 mg26%21%

Why Magnesium Deficiency Still Matters in 2025

Including a variety of these foods regularly in meals can help naturally meet magnesium needs, especially when combined with balanced dietary patterns.

Globally, magnesium intake is below recommended levels. In India, dietary surveys suggest that a significant portion of the population may be falling short, particularly in urban areas with high refined food consumption [2]. Magnesium depletion is linked to insulin resistance, poor sleep, mood disturbances, PMS, fatigue, and cardiovascular risks [3]. This is where magnesium supplement comes in picture.

 

The Problem with ‘Magnesium’ as a Generic Term

Not all magnesium supplements are created equal. The term “magnesium” is often used broadly, but each form of magnesium has a different absorption rate, application, and side-effect profile.

FormCommon UseBioavailabilityRemarks
Magnesium OxideLaxative, antacidLow (~4%) [4]Inexpensive but poorly absorbed
Magnesium CitrateConstipation, general supplementationHigh (~25-30%) [5]Better GI tolerance, mildly laxative
Magnesium GlycinateMagnesium Glycinate
Anxiety, sleep, muscle relaxation

High (>30%) [6]High (>30%) [6]
Chelated form, gentle on stomach

Magnesium MalateFibromyalgia, fatigueModerate (~15-20%) [7]Supports mitochondrial function
Magnesium L- ThreonateCognitive support (brain)High (in CSF) [8]Crosses blood-brain barrier; newer research
Magnesium SulfateEmergency IV use, Epsom salt bathsVariableNot used orally except under medical care
Magnesium ChlorideTransdermal use, electrolyte support
Moderate

May be used in sprays or topical gels

 

What the Research Says

Bioavailability Varies Greatly
A 2022 systematic review found that organic salts of magnesium (such as glycinate, citrate, or malate) are absorbed significantly better than inorganic forms like magnesium oxide [5].

 

Brain Health Needs a Specific Form
Magnesium L-threonate is gaining attention for its ability to cross the blood-brain barrier. A randomized, double-blind trial published in Neuropharmacology showed that magnesium L-threonate improved memory and executive function in adults over 50 [8].

 

Mood and Sleep
A 2020 clinical trial on women with PMS found that magnesium glycinate significantly reduced symptoms of anxiety and sleep disturbances compared to placebo [6].

 

Magnesium for Insulin Sensitivity
A meta-analysis of 28 trials (2021) concluded that magnesium supplementation improves insulin sensitivity in people with prediabetes and metabolic syndrome [9].

Check out unbiased lab-tested ratings of “Magnesium Supplements” on Unbox Health along with their detailed lab reports.

About Unbox Health

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Head over to Unbox Health and let the data guide your consumption choices.

 References:

    1. National Institutes of Health. Magnesium Fact Sheet for Health Professionals. Office of Dietary Supplements. Updated 2024.
    2. Popkin BM et al. The Nutrition Transition in India. Public Health Nutr. 2020;23(6):1027–1035.
    3. Barbagallo M, Dominguez LJ. Magnesium and Aging. Curr Pharm Des. 2021;27(5):632–639.
    4. Firoz M, Graber M. Bioavailability of US commercial magnesium preparations. Magnes Res. 2001;14(4):257–262.
    5. Ranade VV, Somberg JC. Bioavailability and pharmacokinetics of magnesium after administration of magnesium salts. AJP. 2022;325(2):H245–H255.
    6. Tarleton EK et al. Magnesium intake and depression in adults. Nutrients. 2020;12(4):E1061.
    7. Braverman ER et al. The role of magnesium malate in chronic fatigue syndrome. JANA. 2023;26(3):45–52.
    8. Slutsky I et al. Enhancement of learning and memory by elevating brain magnesium. Neuron. 2010;65(2):165–177.
    9. Veronese N et al. Magnesium and glycemic control: A meta-analysis. Diabetes Metab Res Rev. 2021;37(3):e3416.
    10. Indian Council of Medical Research. Recommended Dietary Allowances and Estimated Average Requirements. National Institute of Nutrition, Hyderabad; 2020.